Role of stress response sigma factor SigG in Mycobacterium tuberculosis.

J. Lee, D. Geiman, W. Bishai
Journal of bacteriology. 2008 190:3 PubMed: 18039768

Abstract: The sigG gene of Mycobacterium tuberculosis was disrupted by homologous recombination, and the genes regulated by SigG were examined by real-time reverse-transcription PCR and microarray studies. The SigG consensus promoter recognition sequence was identified as GCGNGT-N15-18-CGANCA. A DeltasigG mutant was found to be more resistant to mitomycin C treatment than the wild-type strain, indicating that it may be involved in the SOS response in M. tuberculosis.

Described groups:

  • ECF56

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