General description: Proteins from ECF48 are homologous to proteins from the original ECF48 (14%) and are present in Actinobacteria (100%). Members of ECF48 contain C-terminal extensions with a zinc-finger and one transmembrane helix, except in ECF48s2, where the C-terminal extension is shorter and soluble. The length of the C-terminal extension ranges from ~60 aa in ECF48s2 to ~400 aa in ECF48s4.
Genomic context conservation: We found neither a conserved domain in the context of ECF48 nor any putative AS factor.
Promoter motif conservation: The predicted target promoter motifs are not conserved, and we did not find the target promoter predicted for original ECF48 (Huang, Pinto, Fritz, & Mascher, 2015) in our analysis.
Summary: Therefore, it is likely that ECF48, like in the case of original ECF48 (Huang et al., 2015), is regulated by the zinc-finger of its C-terminal extension.
Number of representative ECFs: 93
Number of non-redundant ECFs: 100
Sequences with C-terminal extension: 99.00%
Sequences with N-terminal extension: 1.00%
Overrepresented order: Corynebacteriales [83.87%]
Title | Journal | Year | Authors | PubMed | ECF groups |
---|---|---|---|---|---|
Environmental Sensing in Actinobacteria: a Comprehensive Survey on the Signaling Capacity of This Phylum. | Journal of bacteriology | 2015 | X. Huang, D. Pinto, G. Fritz, T. Mascher | PubMed: 25986905 | ECF122, ECF56, ECF118, ECF128, ECF51, ECF52, ECF132, ECF53, ECF123, ECF125, ECF54, ECF130, ECF131, ECF218, ECF294, ECF48 |