This group dissipated from the ECF classification during the reclassification by [[Casas-Pastor et al.]]!

Taxonomical distribution

This group was found in a broad spectrum of organisms belonging to the phyla Proteobacteria, Bacteroidetes, Actinobacteria, Firmicutes and Plantomycetes (Staroń et al., 2009).

Experimentally studied examples


Genomic context conservation

Genomic context conservation in members of this group was not observed and no putative anti-σ factor was identified (Staroń et al., 2009).

Signaling mechanism


Physiological function



Members of original group ECF24 are present in ECF238, together with members of original ECF44. 84.87% of the members of ECF238 have homology to ECF24.


Rhodius VA, Segall-Shapiro TH, Sharon BD, et al. 2013. Design of orthogonal genetic switches based on a crosstalk map of σs, anti-σs, and promoters. Molecular Systems Biology 9:702.
Staroń A, Sofia HJ, Dietrich S, Ulrich LE, Liesegang H, et al. 2009. The third pillar of bacterial signal transduction: classification of the extracytoplasmic function (ECF) sigma factor protein family. Molecular Microbiology 74 (3): 557–581.
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