Anti-σ factors: Members of ECF132 might be regulated by a putative AS factor encoded in position +1. Most of the proteins in this position contain one transmembrane helix (58.14%, ~100% when looking at the MSA) but no Pfam domain. The only member of ECF131s5 contains extracytoplasmic domains related to sulfolipid transport (Pfam: SfLAP) and hemolysis (Pfam: Bacillus_HBL) (source: Pfam).
Genomic context conservation: Other than the AS factor, genetic neighborhoods of members of ECF131s1 contain a conserved CoA-binding protein in +2 with homology to YccU from E. coli, a protein overproduced when the cells grow in oleic acid, and also a conserved adenylosuccinate synthetase involved in purine biosynthesis and a YjbR domain.
Promoter motif conservation: Promoter motifs are not conserved, which might be due to the few sequences included in each group.
Number of representative ECFs: 175
Number of non-redundant ECFs: 182
Sequences with C-terminal extension: 0.00%
Sequences with N-terminal extension: 1.10%
Overrepresented phylum: Actinobacteria [99.43%]
|Environmental Sensing in Actinobacteria: a Comprehensive Survey on the Signaling Capacity of This Phylum.||Journal of bacteriology||2015||X. Huang, D. Pinto, G. Fritz, T. Mascher||PubMed: 25986905||ECF122, ECF56, ECF118, ECF128, ECF51, ECF52, ECF132, ECF53, ECF123, ECF125, ECF54, ECF130, ECF131, ECF218, ECF294, ECF48|