General description: Members of this group are present in Actinobacteria (100%) mostly in genus Streptomyces and have homology to proteins from original ECF130 (73.85%).
Special features: Original ECF130 contains a putative soluble AS factor in -1 (Huang et al., 2015); nevertheless, we could not find any conserved Pfam domain in this position, proteins in this position do not align well in MSA, and none of the proteins matches any AS factor from the original library (López-García, Yagüe, Gonzalez-Quiñonez, Rioseras, & Manteca, 2018). Therefore, these proteins were not considered putative AS factors.
Genomic context conservation: We could find conserved proteins with a helix-turn-helix domain in the genetic context of members of ECF130.
Promoter motif conservation: Predicted target promoter motifs are not conserved.
Number of representative ECFs: 117
Number of non-redundant ECFs: 130
Sequences with C-terminal extension: 0.00%
Sequences with N-terminal extension: 0.77%
Overrepresented order: Streptomycetales [97.44%]
|The third pillar of bacterial signal transduction: classification of the extracytoplasmic function (ECF) sigma factor protein family.||Molecular microbiology||2009||A. Staroń, H. Sofia, S. Dietrich, L. Ulrich, H. Liesegang, T. Mascher||PubMed: 19737356||ECF103, ECF21, ECF123, ECF51, ECF39, ECF281, ECF102, ECF130, ECF122, ECF291, ECF15, ECF242, ECF22, ECF285, ECF106, ECF27, ECF31, ECF240, ECF114, ECF16, ECF38, ECF41, ECF105, ECF116, ECF111, ECF03, ECF239, ECF42, ECF294, ECF17, ECF11, ECF29, ECF235, ECF293, ECF118, ECF265, ECF30, ECF23, ECF14, ECF249, ECF18, ECF115, ECF290, ECF25, ECF121, ECF02, ECF120, ECF289, ECF28, ECF243, ECF19, ECF43, ECF107, ECF12, ECF32, ECF36, ECF292, ECF286, ECF271, ECF26, ECF40, ECF56, ECF33|
|Environmental Sensing in Actinobacteria: a Comprehensive Survey on the Signaling Capacity of This Phylum.||Journal of bacteriology||2015||X. Huang, D. Pinto, G. Fritz, T. Mascher||PubMed: 25986905||ECF122, ECF56, ECF118, ECF128, ECF51, ECF52, ECF132, ECF53, ECF123, ECF125, ECF54, ECF130, ECF131, ECF218, ECF294, ECF48|