ECF117

This group dissipated from the ECF classification during the reclassification by [[Casas-Pastor et al.]]!

Taxonomical distribution

This group of σ factors is restricted to Bacteroidetes (Staroń et al., 2009).

Experimentally studied examples

None.

Genomic context conservation

The ECF117 σ factors are putatively co-transcribed with their cognate anti-σ factors but the genomic context conservation does not extend beyond these.

Signaling mechanism

The putative ECF117 cognate anti-σ factor is a soluble protein containing a ZAS domain (Staroń et al., 2009), indicative of a regulatory mechanism relying on conformational changes. Nevertheless, experimental evidence supporting this hypothesis has so far not been gathered.

Physiological function

Unknown.

Re-classification

Members of ECF117 are part of ECF293, together with ECF13 and ECF101. 9.46% of the proteins from ECF293 have homology to original ECF117.

References

Staroń A, Sofia HJ, Dietrich S, Ulrich LE, Liesegang H, et al. 2009. The third pillar of bacterial signal transduction: classification of the extracytoplasmic function (ECF) sigma factor protein family. Molecular Microbiology 74 (3): 557–581.
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