General description: ECF107 is composed by a single subgroup with homology to original ECF107 (98.96%) and present in Firmicutes (100%) from genus Bacillus in organisms such as B. cereus, B. anthracis and B. thuringiensis.
Genetic context conservation: Only five proteins from representative/reference genomes are part of ECF107, making difficult the extraction of meaningful conclusions. These proteins contain a DUF4199 in +2, a DUF5065 in +3, a peptidase family M28 in +4, a tRNA synthetases class I (R) with a DALR anticodon binding domain and an arginyl tRNA synthetase N-terminal domain in -1, a DUF1934 in -2, a LD-carboxypeptidase in -3, a DUF1093 in -4 and a phosphotransferase system EIIC in -5.
Anti-σ factors: In agreement with original ECF017 (Staroń et al., 2009), we observed that position +1 and +2 of the genetic context of members of ECF107 contain a 2-transmembrane helix and 3-transmembrane helix proteins (100%), respectively. Proteins in +1 and +2 are not homologous in the cytoplasmic region, but they could be both AS factors as previously suggested (Staroń et al., 2009).
Promoter motif conservation: Predicted target promoter motifs are not conserved.
Number of representative ECFs: 32
Number of non-redundant ECFs: 96
Sequences with C-terminal extension: 0.00%
Sequences with N-terminal extension: 2.08%
Overrepresented order: Bacillales [96.88%]
|The third pillar of bacterial signal transduction: classification of the extracytoplasmic function (ECF) sigma factor protein family.||Molecular microbiology||2009||A. Staroń, H. Sofia, S. Dietrich, L. Ulrich, H. Liesegang, T. Mascher||PubMed: 19737356||ECF103, ECF21, ECF123, ECF51, ECF39, ECF281, ECF102, ECF130, ECF122, ECF291, ECF15, ECF242, ECF22, ECF285, ECF106, ECF27, ECF31, ECF240, ECF114, ECF16, ECF38, ECF41, ECF105, ECF116, ECF111, ECF03, ECF239, ECF42, ECF294, ECF17, ECF11, ECF29, ECF235, ECF293, ECF118, ECF265, ECF30, ECF23, ECF14, ECF249, ECF18, ECF115, ECF290, ECF25, ECF121, ECF02, ECF120, ECF289, ECF28, ECF243, ECF19, ECF43, ECF107, ECF12, ECF32, ECF36, ECF292, ECF286, ECF271, ECF26, ECF40, ECF56, ECF33|